To pilot my endeavours to new horizons, I navigate along a solid scientific trajectory.
I am a Biochemist and innovator, driven by the passion for
understanding biological systems and translating science into solutions.
Christian C. Gruber, Innophore headquarter, 2021
Life itself depends on the interactions of biomolecules, which are three-dimensional, flexible objects.
My research focuses on understanding their behaviours. In my research group and in my company, we study the structural, functional, dynamic and thermodynamic properties of biological systems using computational methods such as structural bioinformatics, data mining and artificial intelligence. We employ various incarnations of our “Catalophore” approach, a method describing the multivariate, volumetric property-fields projected by biomolecules into their environment. These property fields are, by principle and design, independent of the underlying biomolecular structure, allowing analysis beyond sequence and structure. Combined with modern high-performance computing techniques, this enables a deeper understanding of biological processes and allows to boost drug and protein research applications for biotech, biomedicine and pharmaceutical industry.
“An estimated 54 billion molecules were screened by 130 teams representing more than 500 scientists from the world’s top institutions. The VirtualFlow team, consisting of scientists from the US (Harvard, DFCI, Google and University of California, Berkeley), Austria (Innophore), Germany (Max Planck Institute and Technical University of Berlin) and Ukraine (Enamine and Chemspace), is now in the finalist phase, competing with the few remaining drug discovery teams to win the prestigious Covid19 GrandChallenge, organized by the Joint European Disruptive Initiative (JEDI) , the “European DARPA”. It is to be noted that only teams that have submitted drug proposals with real potential to treat Covid-19 have been selected for the finalist round.”
By February 2021, 878 of the most promising molecules have now been synthesised, compounds that were not available in any molecular library in the world. This is an immense and unprecedented undertaking in human history.
The Jedi GrandChallenge Team
“What we know is a drop, what we don’t know is an ocean.”
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Media owner and responsible for the content:
© by Univ.-Ass. Mag. Dr. Christian Gruber, 8160 Weiz
Content: Private Austrian blog with topics of general interest.
Reports are mainly about science, industry, profession,
teaching and digital developments.